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Methotrexate - HealingWell.com Aug 27, 2012 · Methotrexate is a textbook example of why public funding for medical research is so important. No one in the private sector is going to pay for a study to find out how effective the drug is for ulcerative colitis because they won't be able to patent it and make money off it. Drug Interactions With Methotrexate Drug Interactions With Methotrexate. Several medications -- including NSAIDs, phenytoin, and aspirin -- can react negatively with methotrexate. Drug interactions can increase your risk of liver damage, dangerously low white blood cells, toxicity, and other problems.
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Feb 28, 2019 · Methotrexate is a phase-specific substance the main action of which is directed to the S-phase of cell mitosis. It acts generally most effectively on actively increasing tissues, such as malignant cells, bone marrow, fetal cells, skin epithelium, oral and intestinal mucosa as well as urinary bladder cells. As the proliferation of malignant
Antimetabolites, also categorized as steroid-sparing agents, such as azathioprine, methotrexate, mycophenolic acid, and leflunomide are often used as alternatives to corticosteroids.
Methotrexate is not recommended for breast-feeding mothers. Men and women should use effective methods of birth control while taking methotrexate.
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Read/ask questions in our psoriatic arthritis discussion forums, covering topics like treatment, unusual symptoms, coping, caregiving, research, & more! PKU (Phenylketonuria) is a genetic condition that renders the body incapably of breaking down amino acids such as these. These amino acids are left to collect in the body which can increase the risk of brain damage. Methotrexate is a chemotherapeutic agent that is structurally similar to folic acid. It inhibits dihydrofolate reductase.